Visible-light activatable organic CO-releasing molecules (PhotoCORMs) that simultaneously generate fluorophores.
نویسندگان
چکیده
Novel organic photoCORMs based on micelle-encapsulated unsaturated cyclic α-diketones were designed and synthesized. These photoCORMs can be activated by visible light, have potentially low toxicity, allow the delivery of carbon monoxide to be monitored by fluorescence imaging techniques, and thus are useful tools for the study of the biological function of CO.
منابع مشابه
Visible Light-Activated PhotoCORMs
Despite its well-known toxicity, carbon monoxide (CO) is now recognized as a potential therapeutic agent. Its inherent toxicity, however, has limited clinical applications because uncontrolled inhalation of the gas leads to severe systemic derangements in higher organisms. In order to obviate life-threatening effects and administer the gas by bypassing the respiratory system, CO releasing molec...
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 39 شماره
صفحات -
تاریخ انتشار 2013